The functional role of this structuralmotif has been demonstrated by point mutagenesis, including compensatory mutations.
2
Evidence is presented to show that the structuralmotif responsible for the inhibition is the amphipathic alpha-helix.
3
Zinc fingers are a protein structuralmotif that serve as DNA-binding domains in several transcriptional regulatory proteins.
4
Deletion of a critical structuralmotif disrupts tetramer formation and results in loss of Vps74p localization and function.
5
The structure reveals that the eight PUM repeats correspond to eight copies of a single, repeated structuralmotif.
Ús de structure motif en anglès
1
TGA provided single-nucleotide resolution for each binding site and delineated a highly specific sequence and structuremotif for Vts1 binding.
2
Using this representation, a structuremotif corresponds to a labeled clique that occurs frequently among the graphs representing the protein structures.
3
The pairwise distance constraints on each edge in a clique serve to limit the variation in geometry among different occurrences of a structuremotif.
4
Compared with contact graph representations, the number of spurious structuremotifs is greatly reduced.
5
RNA aptamers are structuredmotifs that bind to specific molecules.
6
We present an efficient constrained subgraph mining algorithm to discover structuremotifs in this setting.
7
The HIV-1 model contains all known structuredmotifs and previously unknown elements, including experimentally validated pseudoknots.
8
Structuremotifs are amino acid packing patterns that occur frequently within a set of protein structures.